منابع مشابه
THE EFFECT OF GLUTARALDEHYDE ON CATALASE Biochemical and Cytochemical Studies with Beef Liver Catalase and Rat Liver Peroxisomes
Peroxidatic activity of catalase (E .C .1 .11 .1 .6) was discovered by Keilin and Hartree (1), and it has been firmly established that, catalase oxidizes various substrates such as ethanol, methanol, nitrite, and formate (2-4) . Crystalline beef liver catalase, used as an enzyme tracer (5), and the peroxisomal catalase (6, 7) have been visualized cytochemically by a modification of the 3,3'diam...
متن کاملStudies on Squalene Epoxidase of Rat Liver*
Rat liver microsomes previously heated to 50” for 5 mm accumulate 2,3-oxidosqualene on incubation with squalene. Squalene epoxidase activity can be assayed either with squalene and heated microsomes or with lO,ll-dihydrosqualene and intact microsomes. In common with other monooxygenases, the epoxidase requires TPNH and molecular oxygen. Both a soluble fraction of rat liver and microsomes are ne...
متن کاملStudies on squalene epoxidase of rat liver.
Rat liver microsomes previously heated to 50” for 5 mm accumulate 2,3-oxidosqualene on incubation with squalene. Squalene epoxidase activity can be assayed either with squalene and heated microsomes or with lO,ll-dihydrosqualene and intact microsomes. In common with other monooxygenases, the epoxidase requires TPNH and molecular oxygen. Both a soluble fraction of rat liver and microsomes are ne...
متن کاملTumor necrosis factor/cachectin decreases catalase activity of rat liver.
Tumor bearing hosts and animals treated with endotoxin commonly show a decrease in the catalase activity of the liver and kidney. Since tumor necrosis factor (TNF)/cachectin may play a significant role in these conditions, we investigated its effects on the catalatic and peroxidatic activity of catalase in the liver and kidney of the rat. The activities of glucose-6-phosphate dehydrogenase and ...
متن کاملDifferential effect of 3-amino-1,2,4-triazole on multiple forms of rat liver catalase.
Injection of 3-amino-1,2,4-triazole into rats resulted in a rapid fall of liver catalase activity which gradually returned to the normal level, but the amount of catalase protein determined by the immunochemical method remained constant without any decrease in parallel with the enzyme activity. Inactivation occurred more rapidly with soluble catalase (or Catalase-II) than with catalase in perox...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1963
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)51810-x